The nutritional status of a mother before and during pregnancy is important for a healthy pregnancy outcome. The preconception period is a critical time for improving the nutritional status of pregnant women and preventing pregnancy complications. (MMN) compared to iron folate (IFA). Methodology: A double-blind randomized cohort study was carried out in three districts of Luwuk, South Luwuk, and North Luwuk, Banggai Regency with a total sample of 19 pregnant women given MMN supplementation and IFA supplementation. See the effect of multi- micronutrient supplementation during pregnancy on MDA levels measured several times (preconception, trimester 1, trimester 2, trimester 3). Results: MMN supplementation group MDA levels from preconception (144.43) decreased in trimester 1 (127.60) to trimester 2 (130.94) again until trimester 3 (96.03), while the average IFA supplementation group MDA from preconception (110.54), increased in trimester 1 (153.87) increased again in trimester 2 (172.50) then decreased in trimester 3 (81.75), a decrease in MDA levels was better in the MMN supplementation group.
